Classify Your Proposal for 2015 TBI

We welcome submissions across the spectrum of topics related to the storage, management, analysis, retrieval, and visualization of large molecular data sets in the context of human health and disease. Consistent with last year, there are no pre-defined tracks. Instead, authors are asked to designate keywords for their proposals via the online submission form.

Submission Deadline: September 25, 2014, 11:59 p.m. EDT

These keywords will be used to match proposals to reviewers and to help organize the papers, abstracts and panels that are accepted for the program into groups or tracks. While we recognize no classification scheme is perfect, you will be asked to choose terms that best characterize your proposal. Specific topics of interest include, but are not limited to:

Keywords:

  1. Analysis Pipelines, Workflows, and Data Provenance
  2. Data Querying and Visualization
  3. Data Repositories
  4. Data Standards, Terminologies, and Ontologies
  5. Drug Discovery, Repurposing, and Side-effect Discovery
  6. Epigenomics
  7. Ethical, Legal, and Social Issues Around Big Biological Data
  8. Experimental Data Metadata and Annotation
  9. Genetic/genomic decision support
  10. Genome-environment interactions
  11. Genomics (GWAS, sequencing, etc)
  12. Integrative Omic Analysis
  13. Machine learning
  14. Metabolomics
  15. Molecular Biomarkers
  16. Natural Language Processing and Free Text Data Mining
  17. Next-Generation Sequencing
  18. Omic data in EHRs
  19. Personalized, Genomic, Individualized, P4 Medicine
  20. Precision Medicine
  21. Big Data in Medicine
  22. Deep Phenotyping
  23. Pharmacogenomics
  24. Phenomics and phenome-wide association studies
  25. Proteomics
  26. Systems Biology and Network Analysis
  27. Systems Medicine
  28. Training and Education in Translational Bioinformatics
  29. Transcriptomics
  30. Use of EHRs for Omic research (GWAS, sequencing, etc)

Although the SPC encourages submissions that will appeal to both the translational bioinformatics and clinical research communities, the Joint Summits on Translational Science is considered as a single conference, and submissions should be directed toward either the TBI or the CRI Summit, but not both. Submission of the same proposal to both conferences will lead to both being rejected.

Learning Objectives (LO)

New this year! Each submission at the AMIA 2015 Joint Summits on Translational Science, regardless of the type, will require at least one learning objective as part of the Scholar One submission. You may add additional learning objectives if you believe they are appropriate.

AMIA is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education to physicians. As an accredited provider, AMIA must design our activities to inspire change in physicians. That change may be a difference in knowledge/competence, performance, or in patient outcomes. Educational design in this environment includes creating “outcomes-based learning objectives.” Creators of content should ask themselves, “What do I want the learner to be able to do, or to do better, after participating in my session?”

To write a good learning objective, define the desired outcome of your presentation. Perform a needs assessment: what knowledge gap is your presentation going to fill? Then write the LO to address the gap you just identified.

Examples of well-written learning objectives:

After participating in this session, the learner should be better able to:

  • Reduce clinical “alarm fatigue” in the general medical-surgical unit by determining variables that may safely reduce noncritical telemetry and monitor alarms
  • Formulate an approach to adoption of health information technology for the small physician group practice [From the AMA]
  • Evaluate healthcare information systems, involving: how to collect/store confidential medical records, describe complex relationships between database fields, and query databases to produce the desired information [From the AMA]

Examples of poorly-written learning objectives:

After participating in this session, the learner should be better able to:

  • Define the healthcare protocol for the treatment and prevention of Stage III and IV pressure ulcers and apply to your own practice [Too many verbs; can break it into: 1) Define the healthcare protocol for the treatment of Stage III and IV pressure ulcers; 2) Define the healthcare protocol for the prevention of Stage III and IV pressure ulcers; and 3) Apply this knowledge to their own practice. From the Colorado Foundation for Medical Care]
  • Explain and discuss current initiatives and effective modalities to prevent incidence of complications such as infection or wrong-sided block. [This is a teaching objective. A learning objective on the same topic would be: “Prevent incidence of complications such as infection or wrong-sided block using current initiatives and effective modalities.” [From Winthrop University Hospital]
  • Become familiar with common eye problems. [The outcome is not measurable, there is no action the learner can take, and there is no context regarding the patient’s condition. Better LO: Screen for eye conditions commonly associated with type 2 diabetes. [From the AAFP]

Additional resource: Guide to Writing Objectives for Continuing Medical Education, from Case Western Reserve University School of Medicine: http://casemed.case.edu/cme/documents/learn_obj_jh09-12-05.pdf

Select Your Format

The types of proposals considered and general requirements for each are listed below. All proposals must conform to the format and presentation requirements described herein. See the “Submission File Requirements” section to find more details on page layout, references, etc.

Abstract Submissions (Podium or Poster)

The abstract presentation is the classic vehicle for clinical and biological conference presentations and is provided to allow for the presentation of important results that are not yet ready for a full paper-submission or that are destined for other journal publications in the future. Abstracts describing preliminary research results or results of small-scale studies, illustrating and discussing innovative systems and services, describing experimental and in-practice projects and programs, reporting experiences with educational programs, conceptual models, and other dimensions of clinical research informatics are encouraged.

Individuals will submit an abstract and the SPC will determine whether the submission is appropriate for podium or poster presentation. Authors will be able to state a preference for podium or poster formats. In general, the SPC will select, based on the reviews, the most innovative and impactful abstract submissions for podium presentations. Authors of abstracts accepted for podium presentation will have 15 minutes to present their work at the Summit plus five minutes for questions and discussion. Authors of abstracts not selected for podium presentation may be invited to share their work in a poster presentation format. The poster sessions are a component of the Summit designed to offer direct access to the authors in a way not possible through podium presentations. Each accepted poster will be displayed during a 60-90-minute poster session. At least one author must be present at the poster session. Electrical power is not supplied to individual posters.

An individual may be a first author of only one abstract submission, which can be in press or under consideration for journal publication elsewhere, but may not be under consideration at or previously presented at other conferences with published proceedings.

Your uploaded abstract file must be submitted as a one-page (8.5 x 11 inch) document and must include:

  • The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of all authors
  • A summary of approximately 50 words, which will also be pasted into a text box at the beginning of the online form to be used in the online and print programs
  • A brief Introduction and Background, Methods, Results and Discussion
  • One optional Illustration (Figure or Table), which must fit in the one page limit
  • Given limited space, abstracts are not expected to be fully-referenced. However, references may be included within the one page limit if desired

TBI Design Challenge – NEW

Background:
The growing abundance of omic and phenotypic data needs suitable tools to increase access, integration and use by the broader research community. Applications that integrate different types of data through publicly available data repositories provide support for and advancement of translational research.

Challenge:
For the purpose of supporting translational research to improve our understanding of disease, develop an original framework, rapid prototype or working application for clustering phenotypic and omic information. This should be done, minimally, with respect to Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC) cancers obtained from The Cancer Genome Atlas (TCGA). Although this is a specific application to lung cancer within TCGA, solutions that can be generalized to other cancers/diseases and repositories are preferred.

Requirements:
Paper submission consistent with the existing requirements.
If selected as a candidate, provide a presentation and/or demo during the conference at the designated session.

Judging Process:
A subset of the highest rated Challenge Competition submissions will be nominated using the standard TBI paper review process. Entries will be judged (combination of the paper and presentation) on the following criteria: ease of use; visualization; generalizability; and algorithmic/statistical basis.

Didactic and Interactive Panels – NEW

Panel sessions are designed to present an integrated set of perspectives or experience on a current topic in clinical research informatics. Panel topics may be on a specific aspect of theory, application, policy, trends, or experience pertaining to any aspect of clinical research informatics, or may provide interdisciplinary viewpoints that cut across traditional themes. Panel submissions and final presentations should demonstrate collective reflection and integration of the content presented by each of the panelists or offer engaged forms of dialogue and interaction between panelists and audience. An individual may be the primary organizer of only one panel and may not participate in more than two panels total.

Two types of panels will be considered: didactic or interactive.

  • Didactic panel sessions will be scheduled for 90-minutes and consist of four 15-minute presentations plus 30 minutes for questions and discussion. This type of panel should be limited to four participants and a moderator.
  • Interactive panel sessions will be centered on a current hot or controversial topic and facilitate scholarly debate among presenters incorporating science, practice, and policy themes to improve the conduct of clinical and translational research. No slides will be used.  Instead, the moderator will prepare questions to guide group discussion or debate.

Your uploaded panel submission document must not exceed a maximum of three (8.5 x 11 inch) pages and must include:

  • The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of the panel organizer and all participants
  • An abstract of 150-200 words, describing the panel, which will also be pasted into a text box at the beginning of the online form to be used in the online and print programs
  • A general description of the panel and issue(s) that will be examined
  • A brief description of each panelist’s perspective, plan for the integration of content presented by each panelist, and plan for interaction between panelists and the audience
  • A statement included at the conclusion of the proposal by the panel organizer that all participants have agreed to take part on the panel. A CV for each presenter will also need to be uploaded (“NIH-style” bio-sketch is preferred)

Papers

The Scientific Program Committee solicits papers on the state-of-the-art in clinical research informatics. Authors of accepted papers will have 15 minutes to present their work at the Summit plus 5 minutes for questions and discussion. An individual may be a first author of only one paper submitted for consideration. Proposals must not be in press or under consideration for presentation or publication elsewhere. All accepted papers will be indexed and available in full-text in MEDLINE and PubMed Central as part of the Summit proceedings.

Your submission must not exceed a maximum of five (8.5 x 11 inch) pages and must include:

  • The names, academic degree(s), affiliations, and locations (city, state, and country, if international) of all authors
  • An abstract of 125-150 words, which will also be pasted into a text box at the beginning of the online form to be used in the online and print programs
  • A brief Introduction and Background, Methods, Results and Discussion
  • Illustrations (figures or tables) as needed, which must fit within the five-page limit. Figures and Tables should be placed in the natural flow of the manuscript, not at the end of the document.
  • References must be in Vancouver format

Student Papers

Student Paper is a subtype of Paper.  All the rules applicable to papers are applicable to Student Papers, which, however, have more rules, as specified next. To encourage new ideas and to foster the inclusion of students, the SPC invites students to submit papers that describe complete or nearly complete research or development efforts in informatics. Individuals who are enrolled in a degree granting program, an academic program such as a medical residency, or a post-doctoral training program, as of September 1, 2014, are eligible to enter a paper into the Student Paper Competition. Work performed as part of a large, collaborative effort is acceptable; however, the student paper will be judged on the student’s specific contributions to the project which must be clearly delineated. Only individual students, not groups, may submit papers for consideration in the student paper competition. Preparation of a manuscript must be entirely the work of the student. Co-authorship is usually limited to the student’s academic advisor. Submissions from international students are encouraged.

Student paper submissions will be reviewed through the SPC’s standard paper review process. In addition, all accepted student papers will be reviewed by a subcommittee of selected SPC members for consideration for student paper awards. Selected finalists will present their work at an award competition session (date/time-TBA). Entrants must attend the award competition session to present. The Awards Subcommittee members will observe and rate the presentations. A winner will be selected based upon the significance, innovation, and quality of the written paper and presentation.

It is the responsibility of the submitting student to ensure that his/her paper is correctly identified as a student paper proposal. Papers submitted for consideration in the Student Paper Competition must adhere to the same requirements as described in the papers category, and in addition, student authors must provide in the online form:

  • The name and address of their training program
  • Clear identification of the primary advisor/mentor of the student submitting the paper
  • A description of that particular author's contribution to the work
  • An attestation of the student's contribution to the manuscript with respect to the following items: (a) the text of the manuscript itself; (b) the data collected for any analysis; (c) the actual data analysis; (d) the review of the literature; (e) if a system was developed, the role of the student in the coding/development of the system; and (f) the evaluation of the results and the formation of the conclusion
  • The student will be asked to e-sign an attestation in the online form verifying that all information provided is accurate. This action will generate an email to the primary advisor asking for his/her e-signature as well.

Peer-based Learning Workshop

As a result of comments received during the 2014 Joint Summits Town Hall meeting, we created a new format for 2015 with a specific focus on “Resources for Clinical and Translational Research”. The new Peer-Based Learning Workshops are designed for demonstrations and discussions of operational information systems used in clinical and translational research. The workshop length may be 90 minutes (minimum) or 180 minutes (maximum) based on the need. If 180 minutes are approved, the workshop will be presented as two consecutive 90-minute sessions to align with the Summit schedule.  The focus of these workshops is to encourage participation by researchers and practitioners from national initiatives, such as the Clinical and Translational Science Awards (CTSA), Electronic Medical Records and Genomics (eMERGE), the national Patient Centered Clinical Research Network (PCORNet), Newborn Screening Translational Research Network (NBSTRN), UK Clinical Research Network (UKCRN), NCI National Clinical Trials Network (NCTN), Rare Disease Clinical Research network (RDCRN), etc., with an emphasis on tools and resources as topics and hands-on interaction with attendees. Proposals of this type must not exceed a maximum of three pages in length and must include:

  • The names, academic degree(s), affiliations, and locations (city, state/province, and country, if international) of all instructors
  • An opening summary of 250-300 words that describes the content of the workshop
  • An outline of topics to be covered
  • The required length of the workshop
  • Specific educational objectives that participants can expect to achieve
  • A description of who should attend (e.g., clinicians, educators, leaders in healthcare or other organizations, researchers, policy-makers, IT professionals)
  • An indication of the level or combination of levels of the content (percentage of basic, intermediate, and advanced material covered)
  • A description of prerequisites, if any
  • Experience of instructors in teaching similar content
  • A curriculum vitae or biosketch for each instructor will need to be uploaded as a separate file. (“NIH-style” biosketch is preferred.)

Pre-Meeting Tutorials

Half-day tutorials are dedicated to in-depth lectures of special topics and interests of relevance to translational bioinformatics and clinical research informatics. Tutorials will provide three and one half hours of instruction, from 8:30 a.m. until 12:00 p.m. There are three half-day slots available on Monday, March 23, only.  Expanding the total number of slots available is not possible because space is limited in the hotel. 

The SPC seeks a balance between tutorials that address essential core informatics theory, principles, or methods, with those that address practical applications, current issues, and emerging trends and developments in informatics. Tutorials range from the general introductory level through specialized advanced treatments. All instructors must be available to present their tutorial on Monday, March 23, and should confirm their availability for that date.

A maximum of two presenters is recommended for pre-meeting tutorials.  Tutorial proposals must not exceed a maximum of four pages in length and must include:

  • The names, academic degree(s), affiliations, and locations (city, state/province, and country, if international) of all instructors
  • An opening summary of 250-300 words that describes the content of the tutorial
  • An outline of topics to be covered
  • Specific educational objectives that participants can expect to achieve
  • A description of who should attend (e.g., clinicians, educators, leaders in healthcare or other organizations, researchers, policy makers, IT professionals)
  • An indication of the level or combination of levels of the content (percentage of basic, intermediate, and advanced material covered)
  • A description of prerequisites, if any
  • Experience of instructors in teaching similar content
  • A curriculum vitae or biosketch for each instructor will need to be uploaded as a separate file. (“NIH-style” biosketch is preferred.)

General Submission File Requirements

Adherence to the following requirements ensures a consistency that facilitates a successful review process. Complete the online form as instructed and attach your manuscript file in compliance with the requirements noted below:

  • File must be in PDF format
  • Adhere to the page length restrictions stated in the category descriptions; submissions violating the page length restrictions will be rejected without review
  • Format for 8.5 x 11 inch paper size with one-inch margins left, right, top and bottom
  • Place the title in 14 point Times New Roman typeface, single column, bold, centered, upper and lower case using initial capitals for each word in the title other than articles and prepositions
  • Below the title include the names, credentials, institutions and locations of the author(s) or panelists, exactly as they are to appear in the on-line and print programs, using 12 point Times New Roman typeface, single-column, bold, centered, upper and lower case using appropriate capitals
  • Include the main text of the proposal file single-spaced in 10 point Times New Roman typeface, justified, one-column format
  • Do not number individual pages
  • Remove all “track changes” markings, then disable track changes before uploading
  • Download submission template for authors

The format of credentials and other author information appearing in the on-line and printed materials is subject to revision by the AMIA office. It is the responsibility of the first author of each proposal to provide full and accurate information about all authors named.

Reference Format

Use the following reference format: Cite all references in the text, tables or figure legends. In the text, use eight-point superscript if possible to indicate reference numbers; if not possible, use 10 point numbers in square brackets. Under a centered heading “References” at the end of the proposal, provide a list of references cited, in order of occurrence in the manuscript, and with titles using initial capital only. List all authors of any cited work when there are six or fewer authors; if more than six, list only the first three followed by “et al.” Follow the Vancouver Style see www.icmje.org/index.html external link. References must fit within the allotted page(s).

Industry Submissions

Industry-authored and industry-client collaborative papers, panels or abstract presentations are welcome. No special proposal designation is required. All industry proposals will follow the existing review processes.

Submission Process and Deadlines

All proposals must be submitted through the submission site in accordance with the following deadline:

September 25, 2014, 11:59 p.m. EDT

All submissions must be made through the submission site external link.

For all submission categories, you will need to complete the online form as instructed and upload your abstract file in compliance with directions provided in this document. Decisions for all submissions will be announced in late November/mid-December.