• April 7 - 11, San Francisco

    2014 Joint Summits on Translational Science

2014 Joint Summits Birds-of-a-Feather Sessions

TBI Sessions

Tuesday, April 8
7:00 a.m. – 8:15 a.m.

BOF01: SciCast Project

Jessie Tenenbaum, Duke University; Anthony Solomonides, NorthShore University Health System; Judy Logan, Oregon Health & Sciences University

AMIA has been invited to participate in the SciCast project (scicast.org), a prediction market that crowdsources the forecasting of various future innovations in Science and Technology.  The Genomics and Clinical Research Informatics Working Groups are sponsoring the first topic leaders through whom questions will be posed and moderated.  This BOF session will present the project and encourage attendees to pose new questions.

BOF02: Practical Implementation of Pharmacogenomics

Joshua Denny, Vanderbilt University

Recently, a few academic medical centers have started implementing genetic data to guide drug prescribing.  Prospective and reactive genetic models exist.  The NIH Implementing Genomics in Practice (IGNITE) and the Electronic Medical Records and Genomics (eMERGE) Networks seek to propel adoption.  Special considerations are needed into how to represent genetic data, where to store it, how to design decision support and surveillance technologies, and how to education patients and providers.  Early clinical trials highlight the challenges of implementing pharmacogenomics.  This session is designed to gather individuals on the front lines of implementing such systems for an informal discussion.

BOF03: Researching in Big Data

Nicholas Tatonetti, Columbia University

The explosion of available massive omic and clinical data sets have made possible new classes of research reusing or repurposing existing data.  The importance of these data and efforts have been recognized by national and international funding bodies through efforts such as the NIH’s Big Data to Knowledge (BD2K) initiative and data resources such as the Database of Genotypes and Phenotypes (dbGaP) and the Gene Expression Omnibus (GEO). 

CRI Sessions

Thursday, April 10
7:00 a.m. – 8:15 a.m.

BOF04: Collecting Clinical Trial Data Using EHR Structured Forms

Vojtech Huser, National Institutes of Health

Integration of clinical trial data collection into routine care is an ongoing clinical research informatics challenge. For clinical registry studies and certain types of observational trials, it is sometimes possible to directly use form capabilities of the existing EHR system to capture research data. This is possible for studies that do not have study blinding concerns (patient or investigator), existence of incidental findings or research vs. clinical billing issues. This session will be a discussion and exchange of experiences with direct use of EHR system by point of care clinicians/researchers rather than using electronic case report forms in a designated research-only electronic data capture system.

BOF05: Representing Study Eligibility Criteria (SIGEC)

Chunhua Weng, Columbia University; Ida Sim, University of California San Francisco

With the burgeoning adoption of electronic health records (EHRs), vast amounts of clinical data are increasingly available for computational reuse.  It is imperative that the scientific community leverage phenomic data to accelerate clinical research at low cost and large scale.  A critical step toward this goal is matching clinical eligibility criteria to clinical data.  However, this task is complicated by the semantic gap between free-text eligibility criteria and raw clinical data: each criterion has many ways to describe it and a myriad of clinical data points that represent it. To accelerate advances in this important research area, we would like to create a collaborative community to chart the problem space, to define mission-critical tasks, and to develop a "divide-and-conquer" strategy.  We welcome colleagues with interest in formal representations for clinical eligibility criteria and computable phenotype knowledge or with expertise in text-based knowledge engineering to join us in this effort.  We also welcome anyone who is just interested in this topic to join us and share your insights and feedback.

BOF06: Future Directions for the Clinical and Translational Research Informatics Community: Life After the Informatics Key Function Committee

Philip Payne, The Ohio State University; Justin Starren, Northwestern University

With recent changes in the structure and focus on the national CTSA consortium, the TBI and CRI community that had coalesced around the Informatics Key Function Committee (IKFC) has been left without a professional home.  This BoF session will explore next steps related to the sustainability and growth of that community, addressing critical questions such as: 1) should AMIA serve as the new professional home for the activities previously housed in the IKFC? 2) are there other stakeholders who should be engaged in an expanded/renewed community derived from the IKFC? and 3) what existing IKFC or new community-derived activities should an emergent professional home engage in.