January JAMIA Journal Club Webinar

January 12, 2017
Free for AMIA members and students of Academic Forum member institutions; Others: $50
Kavi Wagholikar, MBBS, PhD

SMART-on-FHIR implemented over i2b2

Kavi Wagholikar will discuss this month's JAMIA Journal Club selection:

Wagholikar KB, Mandel JC, Klann JG, et al. SMART-on-FHIR implemented over i2b2. J Am Med Inform Assoc. 2016 Jun 6. pii: ocw079. doi: 10.1093/jamia/ocw079.


Kavishwar Wagholikar, MBBS PhD
Instructor, Harvard Medical School
Assistant in Computer Science, Massachusetts General Hospital, Boston, MA

Kavishwar Wagholikar, MD, PhD, is an Assistant in Computer Science at Massachusetts General Hospital and an Instructor in Medicine at Harvard Medical School. Kavi completed his clinical training – MBBS and PhD – in India, and was a post-doctoral fellow at Mayo Clinic (2011-14).

Dr. Wagholikar is a recipient of a K99/R00 career development award from the National Library of Medicine (2014-19). The objective of his research is to develop a framework for natural language processing (NLP)- enabled CDS. The framework consists of methodologies and tools that will facilitate rapid development of apps for clinical use.


  • 40-minute discussion between the authors and the JAMIA Student Editorial Board moderators including salient features of the published study and its potential impact on practice.
  • 20-minute discussion of questions submitted by listeners via the webinar tools.


  • Follow @AMIAinformatics and #JAMIAJC for Journal Club information.
  • Participants also receive short feedback surveys to evaluate the JAMIA JC webinar.


JAMIA Journal Club managers are JAMIA Student Editorial Board members:

Daniel R. Schlegel, PhD, Department of Biomedical Informatics, University at Buffalo, The State University of New York

Fabricio Kury, MD, Postdoctoral Fellow, US National Library of Medicine


The PubMed citation for the paper under discussion is:

Wagholikar KB, Mandel JC, Klann JG, et al. SMART-on-FHIR implemented over i2b2. J Am Med Inform Assoc. 2016 Jun 6. pii: ocw079. doi: 10.1093/jamia/ocw079.

Fee Statement

Students who are not AMIA members, but whose academic institutions are members of the Academic Forum, are eligible for a complimentary JAMIA Journal Club registration. Please contact Susanne Arnold at susanne@amia.org for the discount code. In the email, please include: full name, Academic Department, and the primary Academic Forum representative of that Academic Department. Note that AMIA Student memberships are $45, which allow access to JAMIA, all JAMIA Journal Clubs, and other webinars of interest to the biomedical informatics community. 

Statement of Purpose

Informatics for Integrating Biology & the Bedside (i2b2) is an open source clinical data analytics platform originally developed under funding from the National Institutes of Health. I2b2 is used at over 140 sites for querying patient data to address research questions.  I2b2 aggregates a copy of the patient data from the electronic health record (EHR), providing query services in parallel to the EHR for research. Thanks to this data copy, the EHR system is not overloaded by research operations, and can focus on clinical operations.  This project provides a platform for executing SMART on FHIR apps on the i2b2 repositories, and provides a pathway to leverage i2b2 for clinical operations, which was not possible previously.

Target Audience

The target audience for this activity is professionals and students interested in biomedical and health informatics.

Learning Objective

After this live activity, the participant should be better able to:

  • Understand the challenges for interoperability.
  • Utilize existing open-source software for running SMART apps.
  • Develop innovative and portable applications in healthcare. 


Kavishwar Wagholikar, MBBS, PhD
Instructor, Harvard Medical School
Assistant in Computer Science, Massachusetts General Hospital, Boston, MA

Accreditation Statement

The American Medical Informatics Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation Statement

The American Medical Informatics Association designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Criteria for Successful Completion

Completion of this live activity is demonstrated by:

  • Viewing the live webinar
  • Optional submission of questions via webinar feature; option to follow @AMIAinformatics and tweet via #JAMIAJC
  • Completion of the evaluation survey emailed at the webinar's conclusion, and 
  • Verification of attendance through the participant's electronic report through the individual login to AMIA Central at www.amia.org. 

The physician participant will be able to generate a CME certificate through the AMIA automated system. 
For a certificate of completion, contact Pesha@amia.org.

Commercial Support

No commercial support was received for this activity.

Disclosure Policy

As a provider accredited by the ACCME, AMIA requires that everyone who is in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest for 12 months prior to the educational activity.

The ACCME considers relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.

Faculty and planners who refuse to disclose relevant financial relationships will be disqualified from participating in the CME activity. For an individual with no relevant financial relationship(s), the participants must be informed that no conflicts of interest or financial relationship(s) exist.

AMIA uses a number of methods to resolve potential conflicts of interest, including: limiting content of the presentation to that which has been reviewed by one or more peer reviewers; ensuring that all scientific research referred to conforms to generally accepted standards of experimental design, data collection, and analysis; undertaking review of the educational activity by a content reviewer to evaluate for potential bias, balance in presentation, evidence-based content or other indicators of integrity, and absence of bias; monitoring the educational activity to evaluate for commercial bias in the presentation; and/or reviewing participant feedback to evaluate for commercial bias in the activity.

Disclosures for this Activity

These faculty, planners, and staff who are in a position to control the content of this activity disclose that they and their life partners have no relevant financial relationships with commercial interests: 

Faculty: Kavishwar Wagholikar
JAMIA Journal Club planners: Daniel R. Schlegel, Fabricio Kury
AMIA staff: Susanne Arnold, Pesha Rubinstein

JAMIA Journal Club planner Michael Chiang discloses the following relevant financial relationships with commercial interests that have occurred within the previous 12 months:
Grants/Research Support: Research to Prevent Blindness; National Institutes of Health
Other Financial or Material Support: Clarity Medical Systems (unpaid member of Scientific Advisory Board)
Consultant: Novartis

Instructions for Claiming CME/CE Credit

CME site (MyAMIA) works best with IE 8 or above version, Chrome, Safari, and Firefox.

  • Login to your account at amia.org; in upper right hand corner, click on AMIA Central
  • Go to “My Events" under Membership/Activities
  • Click “Apply for Credits" for this webinar
  • Follow the instructions on the Credit Registration page. Be sure both drop-down menus say “physician”
  • To print out your certificate, go to "My CME/CE Credits" under Membership/Activities.
  • Physicians will be able to print out or save their CME certificates.
  • Other attendees: if you require a certificate of participation, please contact pesha@amia.org

Contact Info

For questions about content or CE, email pesha@amia.org.