April JAMIA Journal Club Webinar

April 13, 2017
Free for AMIA members and students of Academic Forum member institutions; Others: $50
Katrina M. Romagnoli, PhD

Design and evaluation of a pharmacogenomics information resource for pharmacists

Katrina M. Romagnoli will discuss this month's JAMIA Journal Club selection:

Romagnoli KM, Boyce RD, Empey PE, Ning Y, Adams S, Hochheiser H. Design and evaluation of a pharmacogenomics information resource for pharmacists. J Am Med Inform Assoc. 2017 Feb 26. 


Katrina M. Romagnoli, PhD
Senior User Experience Designer
​Consumer Health Innovation
UPMC Health Plan  
University of Pittsburgh
Pittsburgh, PA

Dr. Romangnoli champions the design, development, use, and improvement of informatics solutions to diverse, complex clinical problems. She has been deeply involved in the development and implementation of informatics solutions to clinical problems in diverse areas of healthcare, including: pharmacogenomics, drug-drug interactions, fall risk reduction in nursing homes, continuity of care in home care nursing, and complex medication administration for the elderly. She uses human factors research and user-centered design methods to improve the usability of informatics resources and tools, to get the right information, into the right person's hands, at the right time, to empower clinicians and other healthcare workers to make the best, safest decisions for patients.

She works as a Sr. User Experience Designer in the Consumer Health Innovation department at the UPMC Health Plan in Pittsburgh and can be found online at https://www.linkedin.com/in/katrina-romagnoli-10819058 and  http://katrinaromagnoli.com/. 


  • 40-minute discussion between the authors and the JAMIA Student Editorial Board moderators including salient features of the published study and its potential impact on practice.
  • 20-minute discussion of questions submitted by listeners via the webinar tools.


  • Follow @AMIAinformatics and #JAMIAJC for Journal Club information.
  • Participants also receive short feedback surveys to evaluate the JAMIA JC webinar.


JAMIA Journal Club managers are JAMIA Student Editorial Board members:

Daniel R. Schlegel, PhD, Visiting Assistant Professor in the Computer Science Department at SUNY Oswego.

Tim Herr, PhD Candidate in Health and Biomedical Informatics, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.


The PubMed citation for the paper under discussion is:

Romagnoli KM, Boyce RD, Empey PE, Ning Y, Adams S, Hochheiser H. Design and evaluation of a pharmacogenomics information resource for pharmacists. J Am Med Inform Assoc. 2017 Feb 26. 

Fee Statement

Students who are not AMIA members, but whose academic institutions are members of the Academic Forum, are eligible for a complimentary JAMIA Journal Club registration. Please contact Susanne Arnold at susanne@amia.org for the discount code. In the email, please include: full name, Academic Department, and the primary Academic Forum representative of that Academic Department. Note that AMIA Student memberships are $45, which allow access to JAMIA, all JAMIA Journal Clubs, and other webinars of interest to the biomedical informatics community. 

Statement of Purpose

Using information about the interaction between genotypes and medications to inform medication and dosage choices can optimize treatment and prevent adverse medication events, yet that knowledge is not regularly applied. Insufficient pharmacogenomics training, complicated terminology, and a rapidly moving field complicate the task, making clinicians of all types uncertain of their ability to make informed decisions about medications with pharmacogenomics implications.

Consequences of not knowing a patient’s genotype and resulting phenotype can be severe, even fatal, as in the death of a breastfed newborn whose mother was an ultra-rapid metabolizer of codeine, which caused her breast milk to contain toxic levels of codeine’s active metabolite, morphine.

As drug information experts poised to support the pharmacogenomics information needs of other clinicians, pharmacists play a key role in pharmacogenomics-informed drug decisions. Multiple pharmacogenomics information resources are available to pharmacists, including the FDA Table of Pharmacogenomic Biomarkers in Drug Labeling and FDA labeling information in the Pharmacogenomics Knowledge Base (PharmGKB), but none of these resources are currently able to provide clinically relevant information at the point of care.
To address this need, Romagnoli et al created a prototype user interface as a first step toward the goal of providing clinically actionable pharmacogenomics information at the point of care.

Target Audience

The target audience for this activity is professionals and students interested in biomedical and health informatics.

Learning Objective

After this live activity, the participant should be better able to:

  • Compare the benefits and limitations of current and potential clinician-focused pharmacogenomics information resources that offer patient-specific drug decision support to clinicians 


Katrina M. Romagnoli, PhD
Senior User Experience Designer
Consumer Health Innovation
UPMC Health Plan  
University of Pittsburgh
Pittsburgh, PA

Accreditation Statement

The American Medical Informatics Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation Statement

The American Medical Informatics Association designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Criteria for Successful Completion

Completion of this live activity is demonstrated by:

  • Viewing the live webinar
  • Optional submission of questions via webinar feature; option to follow @AMIAinformatics and tweet via #JAMIAJC
  • Completion of the evaluation survey emailed at the webinar's conclusion, and 
  • Verification of attendance through the participant's electronic report through the individual login to AMIA Central at www.amia.org. 

The physician participant will be able to generate a CME certificate through the AMIA automated system. 
For a certificate of completion, contact Pesha@amia.org.

Commercial Support

No commercial support was received for this activity.

Disclosure Policy

As a provider accredited by the ACCME, AMIA requires that everyone who is in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest for 12 months prior to the educational activity.

The ACCME considers relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.

Faculty and planners who refuse to disclose relevant financial relationships will be disqualified from participating in the CME activity. For an individual with no relevant financial relationship(s), the participants must be informed that no conflicts of interest or financial relationship(s) exist.

AMIA uses a number of methods to resolve potential conflicts of interest, including: limiting content of the presentation to that which has been reviewed by one or more peer reviewers; ensuring that all scientific research referred to conforms to generally accepted standards of experimental design, data collection, and analysis; undertaking review of the educational activity by a content reviewer to evaluate for potential bias, balance in presentation, evidence-based content or other indicators of integrity, and absence of bias; monitoring the educational activity to evaluate for commercial bias in the presentation; and/or reviewing participant feedback to evaluate for commercial bias in the activity.

Disclosures for this Activity

These faculty, planners, and staff who are in a position to control the content of this activity disclose that they and their life partners have no relevant financial relationships with commercial interests: 

JAMIA Journal Club planners: Daniel R. Schlegel, Tim Herr
AMIA staff: Susanne Arnold, Pesha Rubinstein
Faculty: Katrina M. Romagnoli

JAMIA Journal Club planner Michael Chiang discloses the following relevant financial relationships with commercial interests that have occurred within the previous 12 months:
Grants/Research Support: Research to Prevent Blindness; National Institutes of Health
Other Financial or Material Support: Clarity Medical Systems (unpaid member of Scientific Advisory Board)
Consultant: Novartis

Instructions for Claiming CME/CE Credit

CME site (MyAMIA) works best with IE 8 or above version, Chrome, Safari, and Firefox.

  • Login to your account at amia.org; in upper right hand corner, click on AMIA Central
  • Go to “My Events" under Membership/Activities
  • Click “Apply for Credits" for this webinar
  • Follow the instructions on the Credit Registration page. Be sure both drop-down menus say “physician”
  • To print out your certificate, go to "My CME/CE Credits" under Membership/Activities.
  • Physicians will be able to print out or save their CME certificates.
  • Other attendees: if you require a certificate of participation, please contact pesha@amia.org

Contact Info

For questions about content or CE, email pesha@amia.org.