The Master of Science in Health Informatics (MSHI) program at the Medical University of South Carolina is designed to ensure graduates are prepared (a) to select, implement, use, and evaluate healthcare information systems such as electronic health records (EHRs) and data management and analytic systems; (b) to lead organizational efforts in health informatics and IT; and (c) to apply data analytical skills to transform patient care and the care delivery process. The program offers a thesis option to students interested in conducting health informatics research. As an academic medical center, MUSC is equipped to provide students with firsthand experience in working with our clinical data warehouse and in conducting health informatics research. Our program is also closely aligned with MUSC medical center complex, where clinical and administrative information systems are widely deployed. Students may gain firsthand experience with EHR systems, telemedicine/telehealth, patient portals, mobile technologies, and health information exchange, while collaborating with expert clinicians and researchers in the field. Graduates of the program will be prepared to assume positions as data analytics officers, clinical system analysts, health IT project managers, and chief medical/nursing information officers in hospitals, physician practices, and other health care settings.