The 10x10 at Stanford University provides an introduction to the relevant pharmacology, genomics, experimental methods for high-throughput measurements (sequencing, expression, genotyping), analysis methods for GWAS, chemoinformatics, and natural language processing. Review of key gene classes (cytochromes, transporters, GPCRs), key drugs for which genetics is critical (warfarin, clopidogrel, statins, NSAIDs, neuropsychiatric drugs and cancer drugs). Also reviews resources for pharmacogenomics (PharmGKB, Drugbank, CMAP, and others) as well as issues in doing clinical implementation of pharmacogenomics testing.
The AMIA 10x10 program prepares professionals in the health, biological, pharmaceutical and IT areas to address informatics issues in the workplace. The Stanford course breaks new ground by opening up topics in bioinformatics to the 10x10 program. "Stanford is excited to be a part of the 10x10 program. We are committed to distance learning and have an existing infrastructure for an online MS degree and online graduate certificate program." said Dr. Altman.
Russ Altman, MD, PhD, Professor of Bioengineering, Genetics, Medicine, and Computer Science (by courtesy), and Director of the Biomedical Informatics Training Program, will serve as the director of the Stanford University 10x10 offering. Prof. Altman is the Co-Principal Investigator for Stanford's PharmGKB pharmacogenomics knowledge base (http://www.pharmgkb.org/).
Dr. Alison Fohner, PharmGKB
Sara Hillenmeyer, Stanford Biomedical Informatics
Dr. Natalia Khuri, UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (CERSI)
Dr. Michelle Whirl-Carrillo, PharmGKB