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Topics in Pharmacoinformatics

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Fundamentals in Pharmacogenomics

Websites

  • What Is Pharmacogenomics?
  • How will gene variation be used in predicting drug response?
These questions and more are answered at an NLM Science Primer, a resource designed to aid the novice user.
http://www.ncbi.nlm.nih.gov/About/primer/pharm.html

Public Health Perspectives are presented by the CDC through journal articles, news stories, and slides.
http://www.cdc.gov/genomics/info/perspectives/pharmaco.htm

The PharmGKB is an integrated resource about how variation in human genes leads to variation in our response to drugs.
http://www.pharmgkb.org/

Articles

N Engl J Med. 2003 Feb 6;348(6):538-49. http://www.nejm.org
Pharmacogenomics--drug disposition, drug targets, and side effects.
Evans WE, McLeod HL
Comments in:
· N Engl J Med. 2003 Feb 6;348(6):553-6.
· N Engl J Med. 2003 May 15;348(20):2041-3; author reply 2041-3.

St. Jude Children's Research Hospital and the University of Tennessee Colleges of Pharmacy and Medicine, Memphis 38101-0318, USA. william.evans@stjude.org

N Engl J Med. 2005 Nov 10;335(19):2074-2077 http://www.nejm.org
Health information altruists - a potentially critical resource
Kohaane IS, Altman RB
Ethical concerns in regards to the confidentiality of pharmacogenomic data