AMIA is overseen by a Board of Directors, all of whom are highly respected, nationally recognized informatics leaders. Supported by dozens of committees that provide recommendations, the Board meets bi-monthly and the Executive Committee meets monthly. The Board guides AMIA’s policies and objectives and publishes periodic summaries of board work for members.
A number of Committees form AMIA's infrastructure to oversee various functions within the organization. These meet throughout the year and in person once a year.
Full-time, career-status staff run day-to-day operations from AMIA’s national office in Bethesda, MD.